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Compound Detail

CHEMBL5780212

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CC1CC2CNCCN2c2ncccc21

Basic Information

ChEMBL ID CHEMBL5780212
Phase Preclinical
Structure Type MOL
InChI Key URUOICGPQOEMQJ-UHFFFAOYSA-N
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

203.3
MW (Da)
1.37
ALogP
3
HBA
1
HBD
28.2
PSA (Ų)
0.69
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C12H17N3
MW 203.29
Aromatic Rings 1
Heavy Atoms 15
NP-Likeness -0.63

Activity Summary

Ki 3 meas. best 7.28

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
5-hydroxytryptamine receptor 2C
CHEMBL225
Ki 7.28 7.28 52.5 1
5-hydroxytryptamine receptor 2B
CHEMBL1833
Ki 7.17 7.17 66.9 1
5-hydroxytryptamine receptor 2A
CHEMBL224
Ki 5.97 5.97 1080.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine