Compound Detail
CHEMBL5783751
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CS(C)(=O)=NC(=O)c1cnc(N)c(-c2cc3cc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3s2)c1
Basic Information
| ChEMBL ID | CHEMBL5783751 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KWVSNBQCQKQRHX-UHFFFAOYSA-N |
3
Targets
10
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
582.0
MW (Da)
6.73
ALogP
6
HBA
3
HBD
126.5
PSA (Ų)
0.25
QED
2
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 10 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor beta CHEMBL1913 | IC50 | 8.22 | 7.86 | 6.0 | 3 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 8.22 | 8.02 | 6.0 | 4 |
| Interferon-induced, double-stranded RNA-activated protein kinase CHEMBL5785 | IC50 | 7.16 | 7.16 | 69.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine