Compound Detail
CHEMBL5785412
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Basic Information
| ChEMBL ID | CHEMBL5785412 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ATHHGWSYXBLXOA-MRXNPFEDSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
434.4
MW (Da)
2.45
ALogP
9
HBA
1
HBD
102.5
PSA (Ų)
0.45
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity nerve growth factor receptor CHEMBL2815 | IC50 | 7.26 | 7.26 | 55.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity nerve growth factor receptor | IC50 | = | 55.0 | nM | 7.26 | TrkA Binding Assay: The ability of a compound to bind to TrkA was measured by In... | - |
| High affinity nerve growth factor receptor | IC50 | = | 55.0 | nM | 7.26 | Binding Assay: The ability of a compound to bind to TrkA was measured by Invitro... | - |
| High affinity nerve growth factor receptor | IC50 | = | 55.0 | nM | 7.26 | Binding Assay: The ability of a compound to bind to TrkA was measured by Invitro... | - |
Data from ChEMBL 36 via Core Engine