Compound Detail
CHEMBL5785570
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5785570 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XLASNYKWHJNDIR-CJNGLKHVSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
397.4
MW (Da)
1.69
ALogP
7
HBA
2
HBD
92.0
PSA (Ų)
0.60
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity nerve growth factor receptor CHEMBL2815 | IC50 | 6.0 | 5.9367 | 1000.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity nerve growth factor receptor | IC50 | = | 1000.0 | nM | 6.0 | Binding Assay: The ability of a compound to bind to TrkA was measured by Invitro... | - |
| High affinity nerve growth factor receptor | IC50 | = | 1000.0 | nM | 6.0 | Binding Assay: The ability of a compound to bind to TrkA was measured by Invitro... | - |
| High affinity nerve growth factor receptor | IC50 | = | 1550.0 | nM | 5.81 | TrkA Binding Assay: The ability of a compound to bind to TrkA was measured by In... | - |
Data from ChEMBL 36 via Core Engine