Compound Detail
CHEMBL5786608
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Basic Information
| ChEMBL ID | CHEMBL5786608 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AOLKSRDLCGXTRO-WHCXFUJUSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
382.5
MW (Da)
2.84
ALogP
5
HBA
1
HBD
61.5
PSA (Ų)
0.88
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine-protein kinase ATM CHEMBL3797 | IC50 | 8.82 | 8.235 | 1.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine-protein kinase ATM | IC50 | = | 1.5 | nM | 8.82 | Biological Assay: ATM: Recombinant, full length human FLAG-tagged ATM activity (... | - |
| Serine-protein kinase ATM | IC50 | = | 22.5 | nM | 7.65 | Biological Assay: ATM: Recombinant, full length human FLAG-tagged ATM activity (... | - |
Data from ChEMBL 36 via Core Engine