Compound Detail
CHEMBL5790327
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Basic Information
| ChEMBL ID | CHEMBL5790327 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NHLVZGANYDEFNZ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
431.5
MW (Da)
2.52
ALogP
10
HBA
3
HBD
131.8
PSA (Ų)
0.40
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 8.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Non-receptor tyrosine-protein kinase TYK2 CHEMBL3553 | EC50 | 8.78 | 8.495 | 1.7 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Non-receptor tyrosine-protein kinase TYK2 | EC50 | = | 1.66 | nM | 8.78 | Probe Displacement Assay: The probe displacement assay is conducted as follows: ... | - |
| Non-receptor tyrosine-protein kinase TYK2 | EC50 | = | 6.17 | nM | 8.21 | Probe Displacement Assay: The probe displacement assay is conducted as follows: ... | - |
Data from ChEMBL 36 via Core Engine