Compound Detail
CHEMBL5790536
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Basic Information
| ChEMBL ID | CHEMBL5790536 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OXWKYGRZWVLPOF-XDTLVQLUSA-N |
4
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
276.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 7.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 7.66 | 6.16 | 22.0 | 2 |
| Prolyl endopeptidase FAP CHEMBL4683 | IC50 | 6.19 | 6.19 | 640.0 | 1 |
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 22.0 | nM | 7.66 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Prolyl endopeptidase FAP | IC50 | = | 640.0 | nM | 6.19 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 8 | IC50 | = | 6000.0 | nM | 5.22 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 10000.0 | nM | 5.0 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 4 | IC50 | = | 22000.0 | nM | 4.66 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
Data from ChEMBL 36 via Core Engine