Compound Detail
CHEMBL5790820
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5790820 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DAANKWPDRAFQBB-UHFFFAOYSA-N |
1
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
385.9
MW (Da)
4.03
ALogP
5
HBA
1
HBD
77.2
PSA (Ų)
0.66
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 4.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Monocarboxylate transporter 4 CHEMBL2073663 | IC50 | 4.85 | 4.586 | 14000.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Monocarboxylate transporter 4 | IC50 | = | 14000.0 | nM | 4.85 | Lactate Transport in MCT4-Expressing MDA-MB-453 Breast Cancer Cells: MCT4 may be... | - |
| Monocarboxylate transporter 4 | IC50 | = | 14000.0 | nM | 4.85 | Lactate Transport in MCT4-Expressing MDA-MB-453 Breast Cancer Cells: MCT4 may be... | - |
| Monocarboxylate transporter 4 | IC50 | = | 39000.0 | nM | 4.41 | Assay 2: MCT4-Mediated Lactate Transport in NCI-H358 Lung Adenocarcinoma Cells: ... | - |
| Monocarboxylate transporter 4 | IC50 | = | 39000.0 | nM | 4.41 | MCT4-Mediated Lactate Transport in NCI-H358 Lung Adenocarcinoma Cell: NCI-H358 l... | - |
| Monocarboxylate transporter 4 | IC50 | = | 39000.0 | nM | 4.41 | Biological Activity Assay 2: NCI-H358 lung adenocarcinoma cells may be used to m... | - |
Data from ChEMBL 36 via Core Engine