Compound Detail
CHEMBL5796189
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Basic Information
| ChEMBL ID | CHEMBL5796189 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PNYBHJVQEDZSEB-KRWDZBQOSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
356.4
MW (Da)
0.44
ALogP
6
HBA
3
HBD
122.5
PSA (Ų)
0.67
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 10.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase kinase kinase 14 CHEMBL5888 | Ki | 10.3 | 10.3 | 0.1 | 1 |
| Unchecked CHEMBL612545 | Ki | 9.89 | 9.89 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase kinase kinase 14 | Ki | = | 0.05 | nM | 10.3 | NIK Enzyme Inhibition Assay: The ability of the nuclear factor-kappa B (NF-kB)-i... | - |
| Unchecked | Ki | = | 0.13 | nM | 9.89 | NIK Enzyme Inhibition Assay: The ability of the nuclear factor-kappa B (NF-kB)-i... | - |
Data from ChEMBL 36 via Core Engine