Compound Detail
CHEMBL5801569
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5801569 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GSBXYRRQGOASER-HNNXBMFYSA-N |
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
479.0
MW (Da)
4.60
ALogP
7
HBA
1
HBD
84.4
PSA (Ų)
0.53
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 7.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium channel protein type 8 subunit alpha CHEMBL5202 | IC50 | 7.01 | 6.9825 | 98.0 | 4 |
| Sodium channel protein type 1 subunit alpha CHEMBL1845 | IC50 | 4.97 | 4.97 | 10782.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium channel protein type 8 subunit alpha | IC50 | = | 98.0 | nM | 7.01 | Electrophysiological Assay (In Vitro Assay): Patch voltage clamp electrophysiolo... | - |
| Sodium channel protein type 8 subunit alpha | IC50 | = | 98.0 | nM | 7.01 | Electrophysiological Assay: The following patch voltage clamp electrophysiology ... | - |
| Sodium channel protein type 8 subunit alpha | IC50 | = | 98.0 | nM | 7.01 | Electrophysiological Assay (In Vitro Assay): Sodium currents were measured using... | - |
| Sodium channel protein type 8 subunit alpha | IC50 | = | 127.0 | nM | 6.9 | Sodium Influx Assay (In Vitro Assay): This sodium influx assay employs the use o... | - |
| Sodium channel protein type 1 subunit alpha | IC50 | = | 10782.0 | nM | 4.97 | Sodium Influx Assay (In Vitro Assay): This sodium influx assay employs the use o... | - |
Data from ChEMBL 36 via Core Engine