Compound Detail
CHEMBL5807316
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Basic Information
| ChEMBL ID | CHEMBL5807316 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWDTTWXVJLYAMB-UHFFFAOYSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
454.8
MW (Da)
6.21
ALogP
3
HBA
1
HBD
47.6
PSA (Ų)
0.52
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 9.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| AP2-associated protein kinase 1 CHEMBL3830 | IC50 | 9.17 | 9.17 | 0.7 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| AP2-associated protein kinase 1 | IC50 | = | 0.67 | nM | 9.17 | AAK1 Kinase Assay: The assays were performed in U-bottom 384-well plates. The fi... | - |
| AP2-associated protein kinase 1 | IC50 | = | 0.67 | nM | 9.17 | AAK1 Kinase Assay: The assays were performed in U-bottom 384-well plates. The fi... | - |
| AP2-associated protein kinase 1 | IC50 | = | 0.67 | nM | 9.17 | AAK1 Kinase Assay: The assays were performed in U-bottom 384-well plates. The fi... | - |
| AP2-associated protein kinase 1 | IC50 | = | 0.67 | nM | 9.17 | Kinase Assay: The assays were performed in U-bottom 384-well plates. The final a... | - |
| AP2-associated protein kinase 1 | IC50 | = | 0.67 | nM | 9.17 | AAK1 Kinase Assay: The assays were performed in U-bottom 384-well plates. The fi... | - |
Data from ChEMBL 36 via Core Engine