Compound Detail
CHEMBL5807467
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Basic Information
| ChEMBL ID | CHEMBL5807467 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OMJQMYFFOQKXJX-UHFFFAOYSA-N |
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
338.1
MW (Da)
4.00
ALogP
5
HBA
3
HBD
87.4
PSA (Ų)
0.50
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone deacetylase 11 CHEMBL3310 | IC50 | 8.52 | 8.52 | 3.0 | 1 |
| Histone deacetylase 6 CHEMBL1865 | IC50 | 6.12 | 6.12 | 750.0 | 1 |
| Histone deacetylase 8 CHEMBL3192 | IC50 | 6.12 | 6.12 | 750.0 | 1 |
| Histone deacetylase 7 CHEMBL2716 | IC50 | 5.12 | 5.12 | 7500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histone deacetylase 11 | IC50 | = | 3.0 | nM | 8.52 | HDAC Inhibition Assays: This example describes in vitro inhibition properties of... | - |
| Histone deacetylase 6 | IC50 | = | 750.0 | nM | 6.12 | HDAC Inhibition Assays: This example describes in vitro inhibition properties of... | - |
| Histone deacetylase 8 | IC50 | = | 750.0 | nM | 6.12 | HDAC Inhibition Assays: This example describes in vitro inhibition properties of... | - |
| Histone deacetylase 7 | IC50 | = | 7500.0 | nM | 5.12 | HDAC Inhibition Assays: This example describes in vitro inhibition properties of... | - |
Data from ChEMBL 36 via Core Engine