Compound Detail
CHEMBL5816807
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Basic Information
| ChEMBL ID | CHEMBL5816807 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FFBHFFJDDLITSX-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
2.50
ALogP
5
HBA
2
HBD
88.1
PSA (Ų)
0.83
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 9.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 9.33 | 9.33 | 0.5 | 1 |
| Coagulation factor X CHEMBL244 | Ki | 9.0 | 9.0 | 1.0 | 1 |
| Coagulation factor X CHEMBL3755 | Ki | 8.54 | 8.54 | 2.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 0.47 | nM | 9.33 | Prothrombin Assay: The activity of the compound to be tested against prothrombin... | - |
| Coagulation factor X | Ki | = | 1.01 | nM | 9.0 | Human Coagulation Factor Xa Assay: The inhibitory activity on coagulation factor... | - |
| Coagulation factor X | Ki | = | 2.87 | nM | 8.54 | Rat Coagulation Factor Xa Assay: The inhibitory activity on coagulation factor X... | - |
Data from ChEMBL 36 via Core Engine