Compound Detail
CHEMBL5816843
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5816843 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XDAKIIDAZZJVQY-XIUUYUQXSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
335.4
MW (Da)
2.80
ALogP
7
HBA
3
HBD
90.3
PSA (Ų)
0.59
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog CHEMBL5768 | IC50 | 8.75 | 8.75 | 1.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | IC50 | = | 1.78 | nM | 8.75 | High-Throughput Competitive Fluorescence Polarization (FP) Screening Assay: A hi... | - |
Data from ChEMBL 36 via Core Engine