Use UniProt P97287 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5768 Target Snapshot
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P97287. Use UniProt P97287 as the stable identity anchor, then attach disease evidence before program review.
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Review this target as Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, mapped to UniProt P97287. Sequence length is 331 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Induced myeloid leukemia cell differentiation protein Mcl-1 homolog as ChEMBL target CHEMBL5768, mapped to UniProt P97287. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Induced myeloid leukemia cell differentiation protein Mcl-1 homolog is the right protein anchor across sources, using UniProt P97287 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P97287 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| UniProt Accession | P97287 |
| Component Type | Protein |
| Sequence Length | 331 aa |
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
How to read this target
Review this target as Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, mapped to UniProt P97287. Sequence length is 331 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5936425 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5943032 | 8.94 | IC50 | 1.16 | Preclinical |
| CHEMBL6028567 | 8.85 | IC50 | 1.41 | Preclinical |
| CHEMBL6008347 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL5816843 | 8.75 | IC50 | 1.78 | Preclinical |
| CHEMBL6058327 | 8.71 | IC50 | 1.97 | Preclinical |
| CHEMBL6010934 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL5886469 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL5924358 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL5872346 | 8.54 | IC50 | 2.9 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 14 assays, 95 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 83 | 6.3 |
| cell-based format | 4 | 11 | 5.2 |
| assay format | 3 | 1 | 5.0 |