Compound Detail
CHEMBL5886469
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Basic Information
| ChEMBL ID | CHEMBL5886469 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CVONJEGVLJAUIO-UTYDHLRSSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
359.4
MW (Da)
3.27
ALogP
7
HBA
3
HBD
90.3
PSA (Ų)
0.58
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog CHEMBL5768 | IC50 | 8.62 | 8.62 | 2.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | IC50 | = | 2.4 | nM | 8.62 | High-Throughput Competitive Fluorescence Polarization (FP) Screening Assay: A hi... | - |
Data from ChEMBL 36 via Core Engine