Compound Detail
CHEMBL5821218
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Basic Information
| ChEMBL ID | CHEMBL5821218 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LMRWAAOIILTZEU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
399.5
MW (Da)
4.59
ALogP
5
HBA
0
HBD
47.4
PSA (Ų)
0.47
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta CHEMBL5554 | IC50 | 8.8 | 8.8 | 1.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | IC50 | = | 1.58 | nM | 8.8 | HTRF In vitro Profiling Assay: PI3Kinase Reaction Buffer was prepared by dilutin... | - |
Data from ChEMBL 36 via Core Engine