Compound Detail
CHEMBL5822152
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)(C)OC(=O)Nc1ccc(C2=NN(C(=O)c3ccc([N+](=O)[O-])cc3)C(c3ccco3)C2)cc1
Basic Information
| ChEMBL ID | CHEMBL5822152 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZGKIFXWAZVFXAQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
476.5
MW (Da)
5.53
ALogP
7
HBA
1
HBD
127.3
PSA (Ų)
0.38
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Apoptosis regulator Bcl-2/Beclin-1 CHEMBL6066579 | IC50 | 5.91 | 5.91 | 1244.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Apoptosis regulator Bcl-2/Beclin-1 | IC50 | = | 1244.0 | nM | 5.91 | High-Throughput Assay: A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to direc... | - |
Data from ChEMBL 36 via Core Engine