Compound Detail
CHEMBL582932
DITHIODIMORPHOLINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL582932 |
| Name | DITHIODIMORPHOLINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HLBZWYXLQJQBKU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
236.4
MW (Da)
0.86
ALogP
6
HBA
0
HBD
24.9
PSA (Ų)
0.53
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.95
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Monoglyceride lipase CHEMBL4191 | IC50 | 4.95 | 4.95 | 11220.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Monoglyceride lipase | IC50 | = | 11220.18 | nM | 4.95 | Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid ... | 19883085 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19883085 | 10.1021/jm901323s | Monoglyceride lipase | 2 |
| 20222671 | 10.1021/jm901757t | MDA-MB-231 | 2 |
| 19883085 | 10.1021/jm901323s | Fatty-acid amide hydrolase 1 | 1 |
| 20222671 | 10.1021/jm901757t | MCF7 | 1 |
| 20222671 | 10.1021/jm901757t | T47D | 1 |
| 20222671 | 10.1021/jm901757t | ADMET | 1 |
Data from ChEMBL 36 via Core Engine