Compound Detail
CHEMBL584413
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Basic Information
| ChEMBL ID | CHEMBL584413 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VPDWLTLORANIAR-CVEARBPZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
369.3
MW (Da)
4.26
ALogP
2
HBA
2
HBD
58.2
PSA (Ų)
0.81
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 CHEMBL2736 | EC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 | EC50 | = | 10000.0 | nM | 5.0 | Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coe... | 19640716 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19640716 | 10.1016/j.bmcl.2009.07.072 | Metabotropic glutamate receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine