Compound Detail
CHEMBL5848788
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5848788 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JMZYPZQWJABIMF-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
323.3
MW (Da)
1.90
ALogP
4
HBA
2
HBD
92.7
PSA (Ų)
0.50
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Triple specificity protein phosphatase PtpB CHEMBL6066201 | IC50 | 7.64 | 7.64 | 23.0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 11 CHEMBL3864 | IC50 | 4.28 | 4.28 | 52600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Triple specificity protein phosphatase PtpB | IC50 | = | 23.0 | nM | 7.64 | Inhibition Assay: Compounds were tested against mPTPB using the p-nitrophenyl ph... | - |
| Tyrosine-protein phosphatase non-receptor type 11 | IC50 | = | 52600.0 | nM | 4.28 | Inhibition Assay: Compounds were tested against mPTPB using the p-nitrophenyl ph... | - |
Data from ChEMBL 36 via Core Engine