Compound Detail
CHEMBL5850435
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Basic Information
| ChEMBL ID | CHEMBL5850435 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SHNZBLYIDWZCHE-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
446.6
MW (Da)
5.14
ALogP
5
HBA
2
HBD
75.2
PSA (Ų)
0.31
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.28
Ki 1 meas. best 7.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | Ki | 7.71 | 7.71 | 19.3 | 1 |
| Somatostatin receptor type 3 CHEMBL2028 | EC50 | 7.28 | 7.28 | 52.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | Ki | = | 19.3 | nM | 7.71 | Radioligand Binding Assay: Competitive radioligand binding experiments were perf... | - |
| Somatostatin receptor type 3 | EC50 | = | 52.8 | nM | 7.28 | Activity Assays: Measurement of forskolin stimulated inhibition of cAMP was perf... | - |
Data from ChEMBL 36 via Core Engine