Compound Detail
CHEMBL5854466
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Basic Information
| ChEMBL ID | CHEMBL5854466 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SISBABDTDWWCKF-UHFFFAOYSA-N |
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
402.5
MW (Da)
4.93
ALogP
4
HBA
2
HBD
71.5
PSA (Ų)
0.56
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 6 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.26 | 6.26 | 550.0 | 1 |
| Lysine-specific demethylase 4C CHEMBL6175 | IC50 | 6.26 | 6.26 | 550.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | Enzymatic Assay: The ability of test compounds to inhibit the activity of JMJD2C... | - |
| Unchecked | IC50 | = | 550.0 | nM | 6.26 | JMJD2C Assay: The ability of test compounds to inhibit the activity of JMJD2C wa... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET): The ability of t... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | JMJD2C Assay: The ability of test compounds to inhibit the activity of JMJD2C wa... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET): JMJD2C: The abil... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | In Vitro Enzyme Inhibition Assay: JMJD2C: The ability of test compounds to inhib... | - |
Data from ChEMBL 36 via Core Engine