Compound Detail
CHEMBL5856899
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Basic Information
| ChEMBL ID | CHEMBL5856899 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PXESZBHBYSOLEN-MFMILTCTSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
2.72
ALogP
4
HBA
3
HBD
96.4
PSA (Ų)
0.63
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leucyl-cystinyl aminopeptidase CHEMBL2693 | IC50 | 8.31 | 8.31 | 4.9 | 1 |
| Leucyl-cystinyl aminopeptidase CHEMBL3712 | IC50 | 8.23 | 8.23 | 5.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leucyl-cystinyl aminopeptidase | IC50 | = | 4.9 | nM | 8.31 | Inhibition Assay: The inventors have assumed that inhibition of nocturnal activi... | - |
| Leucyl-cystinyl aminopeptidase | IC50 | = | 5.9 | nM | 8.23 | Inhibition Assay: The inventors have assumed that inhibition of nocturnal activi... | - |
Data from ChEMBL 36 via Core Engine