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Compound Detail

CHEMBL5856977

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CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCc2c(C#C[Si](C)(C)C)cccc21

Basic Information

ChEMBL ID CHEMBL5856977
Phase Preclinical
Structure Type MOL
InChI Key XTBVWWRXYVWTQH-FQEVSTJZSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

412.6
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H32N2O3Si
MW 412.61

Activity Summary

IC50 2 meas. best 5.26

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Ubiquitin carboxyl-terminal hydrolase isozyme L1
CHEMBL6159
IC50 5.26 5.26 5500.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine