Compound Detail
CHEMBL5869713
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5869713 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WTTUGTZNJAQTRA-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
464.6
MW (Da)
3.04
ALogP
8
HBA
0
HBD
59.7
PSA (Ų)
0.41
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 7.59
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL217 | Ki | 7.59 | 7.59 | 25.5 | 1 |
| Histamine H1 receptor CHEMBL4701 | Ki | 6.81 | 6.81 | 154.0 | 1 |
| 5-hydroxytryptamine receptor 7 CHEMBL3223 | Ki | 6.22 | 6.22 | 606.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | Ki | = | 25.5 | nM | 7.59 | Receptor Binding Assay: D2:Procedures(1) The prepared membrane was applied with ... | - |
| Histamine H1 receptor | Ki | = | 154.0 | nM | 6.81 | Receptor Binding Assay: Histamine H1: (1) The prepared membrane was applied with... | - |
| 5-hydroxytryptamine receptor 7 | Ki | = | 606.0 | nM | 6.22 | Receptor Binding Assay: 5-HT7: (1) The prepared membrane was applied with buffer... | - |
Data from ChEMBL 36 via Core Engine