Compound Detail
CHEMBL5871401
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Cc1cc([C@@H](NC(=O)c2cc(CN3CCOC3=N)cc(-c3ccc(F)cc3C(F)(F)F)c2F)C2CC2)ccc1F
Basic Information
| ChEMBL ID | CHEMBL5871401 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IPKRPNNLBJEMGE-SANMLTNESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
561.5
MW (Da)
6.75
ALogP
3
HBA
2
HBD
65.4
PSA (Ų)
0.31
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 10.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| WD repeat-containing protein 5 CHEMBL1075317 | Ki | 10.7 | 10.7 | 0.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| WD repeat-containing protein 5 | Ki | = | 0.02 | nM | 10.7 | TR-FRET Binding Assay : A Time-Resolved Fluorescence Resonance Energy Transfer (... | - |
Data from ChEMBL 36 via Core Engine