Compound Detail
CHEMBL5874740
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Basic Information
| ChEMBL ID | CHEMBL5874740 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KPTQBEMJSNBGAL-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
349.4
MW (Da)
2.43
ALogP
7
HBA
1
HBD
95.1
PSA (Ų)
0.59
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysine-specific demethylase 4C CHEMBL6175 | IC50 | 7.26 | 6.5933 | 55.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysine-specific demethylase 4C | IC50 | = | 55.0 | nM | 7.26 | Activity Assay: The ability of test compounds to inhibit the activity of JMJD2C ... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | JMJD2C Assay: The ability of test compounds to inhibit the activity of JMJD2C wa... | - |
| Lysine-specific demethylase 4C | IC50 | = | 550.0 | nM | 6.26 | In Vitro Enzyme Inhibition Assay: The ability of test compounds to inhibit the a... | - |
Data from ChEMBL 36 via Core Engine