Compound Detail
CHEMBL5885279
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Basic Information
| ChEMBL ID | CHEMBL5885279 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SXRCWZOMTWQHSD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
351.4
MW (Da)
1.54
ALogP
7
HBA
3
HBD
117.6
PSA (Ų)
0.64
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MAP kinase-interacting serine/threonine-protein kinase 1 CHEMBL4718 | IC50 | 9.15 | 9.15 | 0.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MAP kinase-interacting serine/threonine-protein kinase 1 | IC50 | = | 0.7 | nM | 9.15 | MKNK1 Kinase High ATP Assay: MKNK1-inhibitory activity at high ATP of compounds ... | - |
Data from ChEMBL 36 via Core Engine