MAP kinase-interacting serine/threonine-protein kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9BUB5. Use UniProt Q9BUB5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BUB5 as the stable identity anchor, then attach disease evidence before program review.
MAP kinase-interacting serine/threonine-protein kinase 1
Review this target as MAP kinase-interacting serine/threonine-protein kinase 1, mapped to UniProt Q9BUB5. Sequence length is 465 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MAP kinase-interacting serine/threonine-protein kinase 1 as ChEMBL target CHEMBL4718, mapped to UniProt Q9BUB5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MAP kinase-interacting serine/threonine-protein kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BUB5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | MAP kinase-interacting serine/threonine-protein kinase 1 |
| UniProt Accession | Q9BUB5 |
| Component Type | Protein |
| Sequence Length | 465 aa |
MAP kinase-interacting serine/threonine-protein kinase 1
Review this target as MAP kinase-interacting serine/threonine-protein kinase 1, mapped to UniProt Q9BUB5. Sequence length is 465 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5855544 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL4879010 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL5984153 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL6052925 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5844466 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL6002798 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4073743 | 9.29 | IC50 | 0.51 | Preclinical |
| CHEMBL5771700 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4076439 | 9.19 | IC50 | 0.65 | Preclinical |
| CHEMBL5885279 | 9.15 | IC50 | 0.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 290 | 824 | 6.8 |
| cell-based format | 52 | 496 | 7.5 |
| assay format | 49 | 74 | 6.8 |