Compound Detail
CHEMBL5892052
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CC[C@H]1OC(=O)[C@H](C)[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)N3CCOCC3)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2[C@H](SCCOc3cc(C(=O)Nc4c(Cl)cncc4Cl)ccc3CO)C(=O)O[C@@]21C
Basic Information
| ChEMBL ID | CHEMBL5892052 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZEQGCNXXRNZHFH-NRCZLJCWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
1084.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 10.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4A CHEMBL254 | IC50 | 10.0 | 10.0 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4A | IC50 | = | 0.1 | nM | 10.0 | Enzyme Assay: PDEs specifically hydrolyze cAMP and/or cGMP and release the produ... | - |
Data from ChEMBL 36 via Core Engine