Compound Detail
CHEMBL5893609
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Basic Information
| ChEMBL ID | CHEMBL5893609 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NDZPRHZISXYFRQ-SVRRBLITSA-N |
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
216.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Arginase-1 CHEMBL1075097 | IC50 | 5.82 | 5.72 | 1500.0 | 3 |
| Arginase-2, mitochondrial CHEMBL1795148 | IC50 | 5.82 | 5.67 | 1500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Arginase-1 | IC50 | = | 1500.0 | nM | 5.82 | Inhibition Assay of Arginase: Inhibition of arginase I (ARG I) and arginase II (... | - |
| Arginase-2, mitochondrial | IC50 | = | 1500.0 | nM | 5.82 | Inhibition Assay of Arginase: Inhibition of arginase I (ARG I) and arginase II (... | - |
| Arginase-1 | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of Arginase: Inhibition of arginase I (ARG I) and arginase II (ARG II... | - |
| Arginase-1 | IC50 | = | 3000.0 | nM | 5.52 | Inhibition Assay: Inhibition of arginase I (ARG I) and arginase II (ARG II) by F... | - |
| Arginase-2, mitochondrial | IC50 | = | 3000.0 | nM | 5.52 | Inhibition Assay: Inhibition of arginase I (ARG I) and arginase II (ARG II) by F... | - |
Data from ChEMBL 36 via Core Engine