Compound Detail
CHEMBL5893645
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5893645 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JWQMHMGGGRQTSY-INIZCTEOSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
431.4
MW (Da)
2.27
ALogP
6
HBA
2
HBD
120.2
PSA (Ų)
0.55
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas. best 7.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL1871 | IC50 | 7.82 | 6.745 | 15.0 | 4 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 15.0 | nM | 7.82 | Gal4-luciferase reporter assay: Briefly, the AR LBD is expressed as a fusion wit... | - |
| Androgen receptor | IC50 | = | 190.0 | nM | 6.72 | mmTV-luciferase reporter assay: An AR-response element is contained within the m... | - |
| Androgen receptor | IC50 | = | 360.0 | nM | 6.44 | Gal4-luciferase reporter assay: Briefly, the AR LBD is expressed as a fusion wit... | - |
| Androgen receptor | IC50 | = | 1000.0 | nM | 6.0 | mmTV-luciferase reporter assay: An AR-response element is contained within the m... | - |
Data from ChEMBL 36 via Core Engine