Compound Detail
CHEMBL589386
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL589386 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RHQAHTWVOWJAQS-XFXZXTDPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
320.4
MW (Da)
4.70
ALogP
2
HBA
0
HBD
8.2
PSA (Ų)
0.66
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | IC50 | 5.84 | 5.84 | 1440.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | IC50 | = | 1440.0 | nM | 5.84 | Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells... | 19945877 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19945877 | 10.1016/j.bmcl.2009.11.037 | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine