Compound Detail
CHEMBL5896450
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5896450 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CSWYTFLVWXTIPC-UHFFFAOYSA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
343.4
MW (Da)
4.76
ALogP
3
HBA
1
HBD
31.9
PSA (Ų)
0.53
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 4 meas. best 9.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alpha-synuclein CHEMBL6152 | Kd | 9.31 | 9.31 | 0.5 | 2 |
| Microtubule-associated protein tau CHEMBL1293224 | Kd | 8.78 | 8.78 | 1.7 | 1 |
| Unchecked CHEMBL612545 | Kd | 8.31 | 8.31 | 4.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alpha-synuclein | Kd | = | 0.49 | nM | 9.31 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Alpha-synuclein | Kd | = | 0.49 | nM | 9.31 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Microtubule-associated protein tau | Kd | = | 1.67 | nM | 8.78 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Unchecked | Kd | = | 4.9 | nM | 8.31 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
Data from ChEMBL 36 via Core Engine