Compound Detail
CHEMBL5899376
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5899376 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PKIOAANQQGQFHH-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
393.2
MW (Da)
5.29
ALogP
5
HBA
1
HBD
89.4
PSA (Ų)
0.51
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Retinoic acid receptor beta CHEMBL2008 | EC50 | 8.7 | 8.7 | 2.0 | 1 |
| Retinoic acid receptor gamma CHEMBL2003 | EC50 | 7.96 | 7.96 | 11.0 | 1 |
| Retinoic acid receptor alpha CHEMBL2055 | EC50 | 7.92 | 7.92 | 12.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Retinoic acid receptor beta | EC50 | = | 2.0 | nM | 8.7 | Transactivation assays: Transcriptional transactivation assays were performed wi... | - |
| Retinoic acid receptor gamma | EC50 | = | 11.0 | nM | 7.96 | Transactivation assays: Transcriptional transactivation assays were performed wi... | - |
| Retinoic acid receptor alpha | EC50 | = | 12.0 | nM | 7.92 | Transactivation assays: Transcriptional transactivation assays were performed wi... | - |
Data from ChEMBL 36 via Core Engine