Compound Detail
CHEMBL5905825
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5905825 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UIHFTURLRBENJM-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
475.9
MW (Da)
3.67
ALogP
6
HBA
1
HBD
72.3
PSA (Ų)
0.50
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL214 | Ki | 8.57 | 8.57 | 2.7 | 1 |
| Alpha-1A adrenergic receptor CHEMBL229 | Ki | 6.54 | 6.54 | 290.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Ki | = | 2.7 | nM | 8.57 | Receptor Binding Assay: 5-HT1A: Radioligand binding was performed using membrane... | - |
| Alpha-1A adrenergic receptor | Ki | = | 290.0 | nM | 6.54 | Radioligand Binding Assay: Alpha1-adrenergic Receptor: Radioligand binding was p... | - |
Data from ChEMBL 36 via Core Engine