Compound Detail
CHEMBL5906744
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5906744 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DJLSOCBGCLKGLV-UHFFFAOYSA-N |
5
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
384.4
MW (Da)
2.88
ALogP
7
HBA
1
HBD
99.2
PSA (Ų)
0.55
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 5 meas. best 7.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A CHEMBL3774298 | Ki | 7.99 | 7.99 | 10.3 | 1 |
| Histone acetyltransferase KAT6B CHEMBL3774300 | Ki | 7.22 | 7.22 | 60.8 | 1 |
| Histone acetyltransferase KAT7 CHEMBL3774299 | Ki | 6.05 | 6.05 | 900.0 | 1 |
| Histone acetyltransferase KAT5 CHEMBL5750 | Ki | 5.22 | 5.22 | 5980.0 | 1 |
| Histone acetyltransferase KAT8 CHEMBL1932912 | Ki | 4.69 | 4.69 | 20600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A | Ki | = | 10.3 | nM | 7.99 | Kat6A Assay 1: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT6B | Ki | = | 60.8 | nM | 7.22 | Kat6B Assay 1: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT7 | Ki | = | 900.0 | nM | 6.05 | Kat7 Assay: A. Compound preparation 1. Prepare 10 mM stock solutions in 100% ... | - |
| Histone acetyltransferase KAT5 | Ki | = | 5980.0 | nM | 5.22 | Kat5 Assay: A. Compound preparation 1. Prepare 10 mM stock solutions in 100% ... | - |
| Histone acetyltransferase KAT8 | Ki | = | 20600.0 | nM | 4.69 | Kat8 Assay: TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
Data from ChEMBL 36 via Core Engine