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Compound Detail

CHEMBL5907138

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CC/C=C/C(C)(O)OCC1(C)C(=O)CCC2(C)C1CCC1(C)C2CCC2C3C(C)C(C)CCC3(C)CCC21C

Basic Information

ChEMBL ID CHEMBL5907138
Phase Preclinical
Structure Type MOL
InChI Key UQBFECUQCTWGFC-GZTJUZNOSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

540.9
MW (Da)
8.98
ALogP
3
HBA
1
HBD
46.5
PSA (Ų)
0.28
QED
2
Ro5 Violations
5
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C36H60O3
MW 540.87
Aromatic Rings 0
Heavy Atoms 39
NP-Likeness 2.55

Activity Summary

Ki 2 meas. best 4.75

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Tyrosine-protein phosphatase non-receptor type 1
CHEMBL335
Ki 4.75 4.75 18000.0 1
Unchecked
CHEMBL612545
Ki 4.66 4.66 22000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine