Compound Detail
CHEMBL5912736
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5912736 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SDQXQGSVVDEHLF-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
454.5
MW (Da)
5.25
ALogP
6
HBA
3
HBD
106.3
PSA (Ų)
0.37
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 8.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor beta CHEMBL1913 | IC50 | 8.05 | 8.05 | 9.0 | 2 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 8.05 | 8.05 | 9.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 | IC50 | = | 9.0 | nM | 8.05 | Biochemical Assay: Biochemical KDR kinase assays were performed in 96 well micro... | - |
| Platelet-derived growth factor receptor beta | IC50 | = | 9.0 | nM | 8.05 | Kinase Assay: PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well... | - |
| Platelet-derived growth factor receptor beta | IC50 | = | 9.0 | nM | 8.05 | PDGFRbeta Kinase Assay: Biochemical PDGFRβ kinase assays were performed in 96 we... | - |
Data from ChEMBL 36 via Core Engine