Compound Detail
CHEMBL591374
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Basic Information
| ChEMBL ID | CHEMBL591374 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LFWQQQGBNHKOSG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
358.4
MW (Da)
4.08
ALogP
5
HBA
1
HBD
77.5
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transcriptional activator Myb CHEMBL5169115 | IC50 | 7.4 | 7.4 | 40.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transcriptional activator Myb | IC50 | = | 40.0 | nM | 7.4 | Inhibition of c-Myb (unknown origin) expressed in HEK293T cells measured after 1... | 36385941 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20485428 | 10.1038/nature09099 | Plasmodium falciparum | 2 |
| - | 10.6019/CHEMBL4513135 | Escherichia coli | 1 |
| 36385941 | 10.1021/acsmedchemlett.2c00403 | Transcriptional activator Myb | 1 |
Data from ChEMBL 36 via Core Engine