Transcriptional activator Myb · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P10242. Use UniProt P10242 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10242 as the stable identity anchor, then attach disease evidence before program review.
Transcriptional activator Myb
Review this target as Transcriptional activator Myb, mapped to UniProt P10242. Sequence length is 640 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcriptional activator Myb as ChEMBL target CHEMBL5169115, mapped to UniProt P10242. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Transcriptional activator Myb is the right protein anchor across sources, using UniProt P10242 as the stable mapping.
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| Preferred Name | Transcriptional activator Myb |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P10242 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcriptional activator Myb |
| UniProt Accession | P10242 |
| Component Type | Protein |
| Sequence Length | 640 aa |
Transcriptional activator Myb
Review this target as Transcriptional activator Myb, mapped to UniProt P10242. Sequence length is 640 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL321336 | 8.06 | IC50 | 8.7 | Preclinical |
| CHEMBL228363 | 8.04 | IC50 | 9.1 | Preclinical |
| CHEMBL5188413 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL5184353 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5198083 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4442805 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL5176572 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5176963 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5198730 | 7.43 | IC50 | 36.8 | Preclinical |
| CHEMBL591374 | 7.4 | IC50 | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 0 | — |
| cell-based format | 1 | 26 | 7.0 |