Compound Detail
CHEMBL5924371
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COc1cc(F)ccc1Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)Nc1cccc(S(N)(=O)=O)c1
Basic Information
| ChEMBL ID | CHEMBL5924371 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VRBWLDAGOWAMFS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
552.4
MW (Da)
5.56
ALogP
5
HBA
2
HBD
107.7
PSA (Ų)
0.39
QED
2
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium channel protein type 10 subunit alpha CHEMBL4017 | IC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium channel protein type 10 subunit alpha | IC50 | = | 1.0 | nM | 9.0 | Electrophysiology Assay: Patch clamp electrophysiology was used to assess the ef... | - |
Data from ChEMBL 36 via Core Engine