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Compound Detail

CHEMBL5936573

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CC1(C)OCCC(=O)OC[C@@H]2[C@H]1CC(=O)[C@]1(C)[C@@H]2CC[C@@]2(C)[C@H](c3ccoc3)OC(=O)[C@H]3O[C@]321

Basic Information

ChEMBL ID CHEMBL5936573
Phase Preclinical
Structure Type MOL
InChI Key DHDCKWIUZCEHEE-FWENLCODSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

472.5
MW (Da)
3.39
ALogP
8
HBA
0
HBD
104.6
PSA (Ų)
0.45
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H32O8
MW 472.53
Aromatic Rings 1
Heavy Atoms 34
NP-Likeness 2.67

Activity Summary

Ki 2 meas. best 5.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 5.22 5.22 6000.0 1
Tyrosine-protein phosphatase non-receptor type 1
CHEMBL335
Ki 5.05 5.05 9000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine