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Compound Detail

CHEMBL5942418

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O=C(Oc1coc(CSc2ccc(Cl)cc2)cc1=O)c1cc(CCc2ccc(Cl)cc2)c[nH]1

Basic Information

ChEMBL ID CHEMBL5942418
Phase Preclinical
Structure Type MOL
InChI Key ZTPNVPVSGTZCTA-UHFFFAOYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

500.4
MW (Da)
6.57
ALogP
5
HBA
1
HBD
72.3
PSA (Ų)
0.22
QED
2
Ro5 Violations
8
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H19Cl2NO4S
MW 500.40
Aromatic Rings 4
Heavy Atoms 33
NP-Likeness -0.54

Activity Summary

IC50 2 meas. best 5.26

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
D-amino-acid oxidase
CHEMBL5485
IC50 5.26 5.26 5500.0 1
D-amino-acid oxidase
CHEMBL6172
IC50 4.26 4.26 55000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine