Compound Detail
CHEMBL5944799
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5944799 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SIPFQZLECWRUCV-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
372.8
MW (Da)
2.65
ALogP
5
HBA
3
HBD
115.1
PSA (Ų)
0.75
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Anoctamin-1 CHEMBL2046267 | EC50 | 8.0 | 7.2333 | 10.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Anoctamin-1 | EC50 | = | 10.0 | nM | 8.0 | Automated Whole-Cell Patch Clamp Assay: Cell Culture and PreparationFisher rat t... | - |
| Anoctamin-1 | EC50 | = | 140.0 | nM | 6.85 | Automated Whole-Cell Patch Clamp Assay to Detect TMEM16A Activity in Recombinant... | - |
| Anoctamin-1 | EC50 | = | 140.0 | nM | 6.85 | Automated Whole-Cell Patch Clamp Assay: Cell Culture and PreparationFisher rat t... | - |
Data from ChEMBL 36 via Core Engine