Compound Detail
CHEMBL5948967
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5948967 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BAHONLRXULXBDR-UHFFFAOYSA-N |
3
Targets
4
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
442.6
MW (Da)
5.19
ALogP
5
HBA
2
HBD
75.2
PSA (Ų)
0.29
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 7.51
EC50 1 meas. best 7.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | Ki | 7.51 | 7.51 | 31.1 | 1 |
| Somatostatin receptor type 3 CHEMBL2028 | EC50 | 7.07 | 7.07 | 85.2 | 1 |
| Somatostatin receptor type 3 CHEMBL2028 | Ki | 5.62 | 5.62 | 2414.0 | 1 |
| Somatostatin receptor type 1 CHEMBL1917 | Ki | 5.39 | 5.39 | 4076.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | Ki | = | 31.1 | nM | 7.51 | Radioligand Binding Assay: Competitive radioligand binding experiments were perf... | - |
| Somatostatin receptor type 3 | EC50 | = | 85.2 | nM | 7.07 | Activity Assays: Measurement of forskolin stimulated inhibition of cAMP was perf... | - |
| Somatostatin receptor type 3 | Ki | = | 2414.0 | nM | 5.62 | Radioligand Binding Assay: Competitive radioligand binding experiments were perf... | - |
| Somatostatin receptor type 1 | Ki | = | 4076.0 | nM | 5.39 | Radioligand Binding Assay: Competitive radioligand binding experiments were perf... | - |
Data from ChEMBL 36 via Core Engine