Compound Detail
CHEMBL5949708
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Basic Information
| ChEMBL ID | CHEMBL5949708 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BLRHUONNMVFXTL-UHFFFAOYSA-N |
1
Targets
3
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
489.0
MW (Da)
6.13
ALogP
7
HBA
2
HBD
87.0
PSA (Ų)
0.40
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 7.3
IC50 1 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Epidermal growth factor receptor CHEMBL203 | IC50 | 7.3 | 7.3 | 50.0 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Kd | 7.3 | 7.3 | 50.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | IC50 | = | 50.0 | nM | 7.3 | Kinase assay: KINOMEscan is based on a competition binding assay that quantitati... | - |
| Epidermal growth factor receptor | Kd | = | 50.0 | nM | 7.3 | Kinase assay: KINOMEscan is based on a competition binding assay that quantitati... | - |
| Epidermal growth factor receptor | Kd | = | 50.0 | nM | 7.3 | Kinase assay: KINOMEscan is based on a competition binding assay that quantitati... | - |
Data from ChEMBL 36 via Core Engine