Compound Detail
CHEMBL5953008
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC1(C)Cc2cc(NC(=O)c3cnn4cccnc34)c(N3CCN(Cc4c[nH]cn4)CC3)cc2O1
Basic Information
| ChEMBL ID | CHEMBL5953008 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IQUVSFJLVSGECK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
472.6
MW (Da)
2.74
ALogP
8
HBA
2
HBD
103.7
PSA (Ų)
0.46
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 8.96 | 8.96 | 1.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 | Ki | = | 1.1 | nM | 8.96 | Biological Assay: Kinase activities were assayed using the Transcreener-Fluorece... | - |
Data from ChEMBL 36 via Core Engine