Compound Detail
CHEMBL5959022
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Basic Information
| ChEMBL ID | CHEMBL5959022 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UTMSBFXWCWGMKU-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
350.4
MW (Da)
2.27
ALogP
4
HBA
3
HBD
99.5
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prolyl hydroxylase EGLN3 CHEMBL5705 | IC50 | 6.17 | 6.17 | 675.0 | 1 |
| Egl nine homolog 1 CHEMBL5697 | IC50 | 5.98 | 5.98 | 1045.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prolyl hydroxylase EGLN3 | IC50 | = | 675.0 | nM | 6.17 | EGLN-1 Activity Assay : The EGLN-1 (or EGLN-3) enzyme activity is determined usi... | - |
| Egl nine homolog 1 | IC50 | = | 1045.0 | nM | 5.98 | EGLN-1 Activity Assay : The EGLN-1 (or EGLN-3) enzyme activity is determined usi... | - |
Data from ChEMBL 36 via Core Engine